Ozempic vs Bydureon
Quick Facts
- Type: GLP-1
- FDA Approval: Ozempic (2017), Bydureon (2012)
- Frequency: Once weekly
Weight Loss Data
- Ozempic: 12-14% in 68 weeks
- Bydureon: 2-4% in 24 weeks
Primary Uses
- •Type 2 Diabetes
- •Weight Management
- •Cardiovascular Risk Reduction
Medication Overview
Ozempic
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2017
Key Benefits
- ✓Significant A1C reduction
- ✓Weight loss support
- ✓Cardiovascular benefits
- ✓Once-weekly dosing
Bydureon
GLP-1Basic Information
- Generic Name: exenatide extended-release
- Manufacturer: AstraZeneca
- FDA Approval: 2012
Key Benefits
- ✓Once-weekly dosing
- ✓No dose titration needed
- ✓Steady medication levels
- ✓Established safety profile
Dosing Information
| Dosing Details | Ozempic | Bydureon |
|---|---|---|
| Starting Dose | 0.25mg | 2mg |
| Maintenance Dose | 0.5mg to 1mg | 2mg |
| Maximum Dose | 2mg | 2mg |
| Schedule | Inject once weekly on the same day each week | Inject once weekly at any time of day |
| Titration | Start with 0.25mg for 4 weeks, then 0.5mg for at least 4 weeks before increasing if needed | No titration required, fixed 2mg dose |
Side Effects
Ozempic
- •Nausea
- •Vomiting
- •Diarrhea
- •Abdominal Pain
- •Constipation
- •Decreased Appetite
Bydureon
- •Nausea
- •Diarrhea
- •Headache
- •Vomiting
- •Constipation
- •Injection Site Reactions
Practical Information
Ozempic
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Widely covered for diabetes, may require prior authorization for weight management
Clinical Results
- Weight Loss: 12-14%
- Study Duration: 68 weeks
- Study: STEP 1 clinical trial
Bydureon
Storage & Handling
- Storage: Refrigerate until use, do not freeze
- Needle Info: Comes with needles in kit
Insurance & Coverage
Generally covered for diabetes treatment
Clinical Results
- Weight Loss: 2-4%
- Study Duration: 24 weeks
- Study: DURATION clinical trials
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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