Ozempic vs Lyxumia
Quick Facts
- Type: GLP-1
- FDA Approval: Ozempic (2017), Lyxumia (2016)
- Frequency: Once weekly
Weight Loss Data
- Ozempic: 12-14% in 68 weeks
- Lyxumia: 2-4% in 24 weeks
Primary Uses
- •Type 2 Diabetes
- •Weight Management
- •Cardiovascular Risk Reduction
Medication Overview
Ozempic
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2017
Key Benefits
- ✓Significant A1C reduction
- ✓Weight loss support
- ✓Cardiovascular benefits
- ✓Once-weekly dosing
Lyxumia
GLP-1Basic Information
- Generic Name: lixisenatide
- Manufacturer: Sanofi
- FDA Approval: 2016
Key Benefits
- ✓Once-daily dosing
- ✓Reduces post-meal glucose levels
- ✓Simple titration schedule
- ✓Can be used with basal insulin
Dosing Information
| Dosing Details | Ozempic | Lyxumia |
|---|---|---|
| Starting Dose | 0.25mg | 10mcg |
| Maintenance Dose | 0.5mg to 1mg | 20mcg |
| Maximum Dose | 2mg | 20mcg |
| Schedule | Inject once weekly on the same day each week | Inject once daily within one hour before the first meal of the day |
| Titration | Start with 0.25mg for 4 weeks, then 0.5mg for at least 4 weeks before increasing if needed | Start with 10mcg daily for 14 days, then increase to 20mcg daily |
Side Effects
Ozempic
- •Nausea
- •Vomiting
- •Diarrhea
- •Abdominal Pain
- •Constipation
- •Decreased Appetite
Lyxumia
- •Nausea
- •Vomiting
- •Diarrhea
- •Headache
- •Dizziness
- •Injection Site Reactions
Practical Information
Ozempic
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Widely covered for diabetes, may require prior authorization for weight management
Clinical Results
- Weight Loss: 12-14%
- Study Duration: 68 weeks
- Study: STEP 1 clinical trial
Lyxumia
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 14 days
- Needle Info: Requires separate pen needles
Insurance & Coverage
Coverage varies by region and insurance plan
Clinical Results
- Weight Loss: 2-4%
- Study Duration: 24 weeks
- Study: GetGoal clinical trial program
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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