Ozempic vs Mounjaro
Quick Facts
- Type: GLP-1 vs GLP-1/GIP
- FDA Approval: Ozempic (2017), Mounjaro (2022)
- Frequency: Once weekly
Weight Loss Data
- Ozempic: 12-14% in 68 weeks
- Mounjaro: 15-20% in 72 weeks
Primary Uses
- •Type 2 Diabetes
- •Weight Management
- •Cardiovascular Risk Reduction
- •Blood Sugar Control
Medication Overview
Ozempic
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2017
Key Benefits
- ✓Significant A1C reduction
- ✓Weight loss support
- ✓Cardiovascular benefits
- ✓Once-weekly dosing
Mounjaro
GLP-1/GIPBasic Information
- Generic Name: tirzepatide
- Manufacturer: Eli Lilly
- FDA Approval: 2022
Key Benefits
- ✓Superior A1C reduction compared to other GLP-1s
- ✓Significant weight loss potential
- ✓Dual-action mechanism
- ✓Once-weekly dosing
Dosing Information
| Dosing Details | Ozempic | Mounjaro |
|---|---|---|
| Starting Dose | 0.25mg | 2.5mg |
| Maintenance Dose | 0.5mg to 1mg | 5mg to 10mg |
| Maximum Dose | 2mg | 15mg |
| Schedule | Inject once weekly on the same day each week | Inject once weekly at any time of day |
| Titration | Start with 0.25mg for 4 weeks, then 0.5mg for at least 4 weeks before increasing if needed | Start with 2.5mg for 4 weeks, then increase to 5mg. Can increase by 2.5mg every 4 weeks |
Side Effects
Ozempic
- •Nausea
- •Vomiting
- •Diarrhea
- •Abdominal Pain
- •Constipation
- •Decreased Appetite
Mounjaro
- •Nausea
- •Diarrhea
- •Decreased Appetite
- •Vomiting
- •Constipation
- •Indigestion
Practical Information
Ozempic
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Widely covered for diabetes, may require prior authorization for weight management
Clinical Results
- Weight Loss: 12-14%
- Study Duration: 68 weeks
- Study: STEP 1 clinical trial
Mounjaro
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 21 days
- Needle Info: Comes with attached hidden needle
Insurance & Coverage
Growing coverage for diabetes, may require prior authorization
Clinical Results
- Weight Loss: 15-20%
- Study Duration: 72 weeks
- Study: SURMOUNT-1 trial
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
Track Your GLP-1 Journey with ShotWise
Get personalized dose tracking, side effect monitoring, and weight loss progress tracking all in one place. Join thousands of others managing their GLP-1 medications effectively.
Download ShotWise