Ozempic vs Saxenda
Quick Facts
- Type: GLP-1
- FDA Approval: Ozempic (2017), Saxenda (2014)
- Frequency: Once weekly
Weight Loss Data
- Ozempic: 12-14% in 68 weeks
- Saxenda: 5-10% in 56 weeks
Primary Uses
- •Type 2 Diabetes
- •Weight Management
- •Cardiovascular Risk Reduction
- •Obesity Treatment
Medication Overview
Ozempic
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2017
Key Benefits
- ✓Significant A1C reduction
- ✓Weight loss support
- ✓Cardiovascular benefits
- ✓Once-weekly dosing
Saxenda
GLP-1Basic Information
- Generic Name: liraglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2014
Key Benefits
- ✓Established weight loss medication
- ✓Well-studied safety profile
- ✓May improve cardiovascular risk factors
- ✓Flexible dosing schedule
Dosing Information
| Dosing Details | Ozempic | Saxenda |
|---|---|---|
| Starting Dose | 0.25mg | 0.6mg |
| Maintenance Dose | 0.5mg to 1mg | 3.0mg |
| Maximum Dose | 2mg | 3.0mg |
| Schedule | Inject once weekly on the same day each week | Inject once daily at any time of day |
| Titration | Start with 0.25mg for 4 weeks, then 0.5mg for at least 4 weeks before increasing if needed | Start with 0.6mg, increase by 0.6mg weekly until reaching 3.0mg |
Side Effects
Ozempic
- •Nausea
- •Vomiting
- •Diarrhea
- •Abdominal Pain
- •Constipation
- •Decreased Appetite
Saxenda
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Injection Site Reactions
- •Low Blood Sugar
Practical Information
Ozempic
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Widely covered for diabetes, may require prior authorization for weight management
Clinical Results
- Weight Loss: 12-14%
- Study Duration: 68 weeks
- Study: STEP 1 clinical trial
Saxenda
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 30 days
- Needle Info: Comes with NovoFine® needles
Insurance & Coverage
Variable coverage for weight management, often requires prior authorization
Clinical Results
- Weight Loss: 5-10%
- Study Duration: 56 weeks
- Study: SCALE clinical trial program
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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