Ozempic vs Wegovy
Quick Facts
- Type: GLP-1
- FDA Approval: Ozempic (2017), Wegovy (2021)
- Frequency: Once weekly
Weight Loss Data
- Ozempic: 12-14% in 68 weeks
- Wegovy: 15-17% in 68 weeks
Primary Uses
- •Type 2 Diabetes
- •Weight Management
- •Cardiovascular Risk Reduction
- •Obesity Treatment
Medication Overview
Ozempic
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2017
Key Benefits
- ✓Significant A1C reduction
- ✓Weight loss support
- ✓Cardiovascular benefits
- ✓Once-weekly dosing
Wegovy
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2021
Key Benefits
- ✓Significant weight loss potential
- ✓Once-weekly dosing
- ✓Improved cardiovascular markers
- ✓Established safety profile
Dosing Information
| Dosing Details | Ozempic | Wegovy |
|---|---|---|
| Starting Dose | 0.25mg | 0.25mg |
| Maintenance Dose | 0.5mg to 1mg | 1mg to 1.7mg |
| Maximum Dose | 2mg | 2.4mg |
| Schedule | Inject once weekly on the same day each week | Inject once weekly on the same day each week |
| Titration | Start with 0.25mg for 4 weeks, then 0.5mg for at least 4 weeks before increasing if needed | Start with 0.25mg, increase every 4 weeks through 0.5mg, 1mg, 1.7mg to reach 2.4mg |
Side Effects
Ozempic
- •Nausea
- •Vomiting
- •Diarrhea
- •Abdominal Pain
- •Constipation
- •Decreased Appetite
Wegovy
- •Nausea
- •Diarrhea
- •Vomiting
- •Constipation
- •Abdominal Pain
- •Headache
Practical Information
Ozempic
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Widely covered for diabetes, may require prior authorization for weight management
Clinical Results
- Weight Loss: 12-14%
- Study Duration: 68 weeks
- Study: STEP 1 clinical trial
Wegovy
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Variable coverage for weight management, often requires prior authorization
Clinical Results
- Weight Loss: 15-17%
- Study Duration: 68 weeks
- Study: STEP clinical trial program
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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