Saxenda vs Bydureon
Quick Facts
- Type: GLP-1
- FDA Approval: Saxenda (2014), Bydureon (2012)
- Frequency: Once daily
Weight Loss Data
- Saxenda: 5-10% in 56 weeks
- Bydureon: 2-4% in 24 weeks
Primary Uses
- •Weight Management
- •Obesity Treatment
- •Type 2 Diabetes
Medication Overview
Saxenda
GLP-1Basic Information
- Generic Name: liraglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2014
Key Benefits
- ✓Established weight loss medication
- ✓Well-studied safety profile
- ✓May improve cardiovascular risk factors
- ✓Flexible dosing schedule
Bydureon
GLP-1Basic Information
- Generic Name: exenatide extended-release
- Manufacturer: AstraZeneca
- FDA Approval: 2012
Key Benefits
- ✓Once-weekly dosing
- ✓No dose titration needed
- ✓Steady medication levels
- ✓Established safety profile
Dosing Information
| Dosing Details | Saxenda | Bydureon |
|---|---|---|
| Starting Dose | 0.6mg | 2mg |
| Maintenance Dose | 3.0mg | 2mg |
| Maximum Dose | 3.0mg | 2mg |
| Schedule | Inject once daily at any time of day | Inject once weekly at any time of day |
| Titration | Start with 0.6mg, increase by 0.6mg weekly until reaching 3.0mg | No titration required, fixed 2mg dose |
Side Effects
Saxenda
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Injection Site Reactions
- •Low Blood Sugar
Bydureon
- •Nausea
- •Diarrhea
- •Headache
- •Vomiting
- •Constipation
- •Injection Site Reactions
Practical Information
Saxenda
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 30 days
- Needle Info: Comes with NovoFine® needles
Insurance & Coverage
Variable coverage for weight management, often requires prior authorization
Clinical Results
- Weight Loss: 5-10%
- Study Duration: 56 weeks
- Study: SCALE clinical trial program
Bydureon
Storage & Handling
- Storage: Refrigerate until use, do not freeze
- Needle Info: Comes with needles in kit
Insurance & Coverage
Generally covered for diabetes treatment
Clinical Results
- Weight Loss: 2-4%
- Study Duration: 24 weeks
- Study: DURATION clinical trials
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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