Saxenda vs Lyxumia
Quick Facts
- Type: GLP-1
- FDA Approval: Saxenda (2014), Lyxumia (2016)
- Frequency: Once daily
Weight Loss Data
- Saxenda: 5-10% in 56 weeks
- Lyxumia: 2-4% in 24 weeks
Primary Uses
- •Weight Management
- •Obesity Treatment
- •Type 2 Diabetes
Medication Overview
Saxenda
GLP-1Basic Information
- Generic Name: liraglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2014
Key Benefits
- ✓Established weight loss medication
- ✓Well-studied safety profile
- ✓May improve cardiovascular risk factors
- ✓Flexible dosing schedule
Lyxumia
GLP-1Basic Information
- Generic Name: lixisenatide
- Manufacturer: Sanofi
- FDA Approval: 2016
Key Benefits
- ✓Once-daily dosing
- ✓Reduces post-meal glucose levels
- ✓Simple titration schedule
- ✓Can be used with basal insulin
Dosing Information
| Dosing Details | Saxenda | Lyxumia |
|---|---|---|
| Starting Dose | 0.6mg | 10mcg |
| Maintenance Dose | 3.0mg | 20mcg |
| Maximum Dose | 3.0mg | 20mcg |
| Schedule | Inject once daily at any time of day | Inject once daily within one hour before the first meal of the day |
| Titration | Start with 0.6mg, increase by 0.6mg weekly until reaching 3.0mg | Start with 10mcg daily for 14 days, then increase to 20mcg daily |
Side Effects
Saxenda
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Injection Site Reactions
- •Low Blood Sugar
Lyxumia
- •Nausea
- •Vomiting
- •Diarrhea
- •Headache
- •Dizziness
- •Injection Site Reactions
Practical Information
Saxenda
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 30 days
- Needle Info: Comes with NovoFine® needles
Insurance & Coverage
Variable coverage for weight management, often requires prior authorization
Clinical Results
- Weight Loss: 5-10%
- Study Duration: 56 weeks
- Study: SCALE clinical trial program
Lyxumia
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 14 days
- Needle Info: Requires separate pen needles
Insurance & Coverage
Coverage varies by region and insurance plan
Clinical Results
- Weight Loss: 2-4%
- Study Duration: 24 weeks
- Study: GetGoal clinical trial program
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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