Trulicity vs Lyxumia
Quick Facts
- Type: GLP-1
- FDA Approval: Trulicity (2014), Lyxumia (2016)
- Frequency: Once weekly
Weight Loss Data
- Trulicity: 2-6% in 52 weeks
- Lyxumia: 2-4% in 24 weeks
Primary Uses
- •Type 2 Diabetes
- •Cardiovascular Risk Reduction
Medication Overview
Trulicity
GLP-1Basic Information
- Generic Name: dulaglutide
- Manufacturer: Eli Lilly
- FDA Approval: 2014
Key Benefits
- ✓Once-weekly dosing
- ✓Ready-to-use pen
- ✓Cardiovascular benefits
- ✓No dose titration required for standard dose
Lyxumia
GLP-1Basic Information
- Generic Name: lixisenatide
- Manufacturer: Sanofi
- FDA Approval: 2016
Key Benefits
- ✓Once-daily dosing
- ✓Reduces post-meal glucose levels
- ✓Simple titration schedule
- ✓Can be used with basal insulin
Dosing Information
| Dosing Details | Trulicity | Lyxumia |
|---|---|---|
| Starting Dose | 0.75mg | 10mcg |
| Maintenance Dose | 1.5mg | 20mcg |
| Maximum Dose | 4.5mg | 20mcg |
| Schedule | Inject once weekly at any time of day | Inject once daily within one hour before the first meal of the day |
| Titration | Start with 0.75mg, can increase to 1.5mg after 4 weeks if needed | Start with 10mcg daily for 14 days, then increase to 20mcg daily |
Side Effects
Trulicity
- •Nausea
- •Diarrhea
- •Vomiting
- •Abdominal Pain
- •Decreased Appetite
- •Indigestion
Lyxumia
- •Nausea
- •Vomiting
- •Diarrhea
- •Headache
- •Dizziness
- •Injection Site Reactions
Practical Information
Trulicity
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 14 days
- Needle Info: Comes with attached hidden needle
Insurance & Coverage
Generally well-covered for diabetes treatment
Clinical Results
- Weight Loss: 2-6%
- Study Duration: 52 weeks
- Study: AWARD clinical trial program
Lyxumia
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 14 days
- Needle Info: Requires separate pen needles
Insurance & Coverage
Coverage varies by region and insurance plan
Clinical Results
- Weight Loss: 2-4%
- Study Duration: 24 weeks
- Study: GetGoal clinical trial program
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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