Wegovy vs Saxenda
Quick Facts
- Type: GLP-1
- FDA Approval: Wegovy (2021), Saxenda (2014)
- Frequency: Once weekly
Weight Loss Data
- Wegovy: 15-17% in 68 weeks
- Saxenda: 5-10% in 56 weeks
Primary Uses
- •Weight Management
- •Obesity Treatment
Medication Overview
Wegovy
GLP-1Basic Information
- Generic Name: semaglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2021
Key Benefits
- ✓Significant weight loss potential
- ✓Once-weekly dosing
- ✓Improved cardiovascular markers
- ✓Established safety profile
Saxenda
GLP-1Basic Information
- Generic Name: liraglutide
- Manufacturer: Novo Nordisk
- FDA Approval: 2014
Key Benefits
- ✓Established weight loss medication
- ✓Well-studied safety profile
- ✓May improve cardiovascular risk factors
- ✓Flexible dosing schedule
Dosing Information
| Dosing Details | Wegovy | Saxenda |
|---|---|---|
| Starting Dose | 0.25mg | 0.6mg |
| Maintenance Dose | 1mg to 1.7mg | 3.0mg |
| Maximum Dose | 2.4mg | 3.0mg |
| Schedule | Inject once weekly on the same day each week | Inject once daily at any time of day |
| Titration | Start with 0.25mg, increase every 4 weeks through 0.5mg, 1mg, 1.7mg to reach 2.4mg | Start with 0.6mg, increase by 0.6mg weekly until reaching 3.0mg |
Side Effects
Wegovy
- •Nausea
- •Diarrhea
- •Vomiting
- •Constipation
- •Abdominal Pain
- •Headache
Saxenda
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Injection Site Reactions
- •Low Blood Sugar
Practical Information
Wegovy
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 56 days
- Needle Info: Comes with NovoFine® Plus needles
Insurance & Coverage
Variable coverage for weight management, often requires prior authorization
Clinical Results
- Weight Loss: 15-17%
- Study Duration: 68 weeks
- Study: STEP clinical trial program
Saxenda
Storage & Handling
- Storage: Refrigerate until first use, then can be stored at room temperature for up to 30 days
- Needle Info: Comes with NovoFine® needles
Insurance & Coverage
Variable coverage for weight management, often requires prior authorization
Clinical Results
- Weight Loss: 5-10%
- Study Duration: 56 weeks
- Study: SCALE clinical trial program
Medical Disclaimer: This comparison is for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider about which medication is right for you. Treatment decisions should be based on your individual medical needs and circumstances.
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